The search for natural biomarkers shed by cancer into the bloodstream is an exciting concept, but in practice it is exceedingly difficult to find the very small amounts of early cancer cell DNA, with trillions of other similar-looking cell DNA around.
Earli is developing a radically new technique originally from Stanford University. Instead of searching, we force cancer cells to make Synthetic Biomarkers that do not belong in the human body, which are then detectable in blood, urine, or breath. Using a similar technique, we will then localize and ultimately destroy the cancer.
A new era of Synthetic Biomarkers is here.
Dr. Sam Gambhir’s wife Aruna had developed breast cancer, and survived it. Then his only 15-year old son Milan developed brain cancer. Meanwhile Sam was urgently searching for new ways to detect and treat cancer. As the founder of Stanford’s Canary Center of Early Cancer Detection, and head of Radiology at the Stanford Clinic, he was looking at natural cancer biomarkers in blood; they were promising, but proving elusive. So Sam flipped the problem on its head and came up with a radically new idea. Four years of lab work ensued to make it work in mice. The solution came too late for his beloved Milan. This deep loss gave Sam a sense of purpose against all odds.
On Thanksgiving Day, Cyriac Roeding, who had sold his previous startup, read Sam’s gripping story and contacted him. He had looked at 200 ideas to find the right next challenge on the intersection of the physical and engineering world. But he had not been as deeply touched by any other mission like Sam’s. The two met on a Saturday morning for breakfast at a local restaurant to talk. It turned out, they lived one minute from each other. More…”
Earli is looking for the world’s best in gene delivery, cell biology, molecular biology, nucleic acids adaptation, translational biology (animal studies), clinical ops (human trials), manufacturing/CMS, and bio AI.
If that’s possibly you, and you like big missions and hard work, *please* let us know.
Are you a potential partner, a journalist, or interested in joining our team?
Or perhaps you just want to say hi.
